Antiviral effects of nisin, lysozyme, lactoferrin and their mixtures against bovine viral diarrhoea virus

Action of lysozyme and nisin mixtures against lactic acid bacteria.

Lysozyme was formulated together with nisin for usage against food spoilage lactobacilli. The mixtures demonstrated improved minimal inhibitory concentrations (MIC), compared to the parent compounds, for many of the bacteria and media tested, including high salt media in which lysozyme lost virtually all of its activity. Synergy was also observed through measurement of the kinetics of bacterial...

Colorimetric lactate dehydrogenase (LDH) assay for evaluation of antiviral activity against bovine viral diarrhoea virus (BVDV) in vitro.

A rapid and sensitive screening assay has been established for in vitro evaluation of antiviral compounds against bovine viral diarrhoea virus (BVDV), which is widely used as a surrogate for hepatitis C virus (HCV). The procedure is based on photospectrometrical assessment for the viability of virus-infected cells via extracellular leakage of lactic dehydrogenase (LDH). The level of LDH in cult...

Economic Impacts, Control and Eradication of Bovine Viral Diarrhoea Virus

Infections with Bovine Viral Diarrhoea Virus (BVD) are endemic in cattle populations worldwide and result in major economic losses; hence, many countries have begun BVD eradication programs. The authors estimated the losses caused by BVD, and the estimated annual losses in 2012 amounted to 4.5 million EUR in Hungary. In a dairy cattle farm with 1000 cows the acute clinical BVD could cause more ...

Prevalence of bovine viral diarrhoea virus antibodies in India.

A study was undertaken regarding the prevalence of bovine viral diarrhoea virus (BVDV) antibodies in bovine sera which tested negative for rinderpest and peste des petits ruminants virus antibodies. The samples were collected between January 1996 and December 1997. A total of 439 samples (327 cattle and 112 buffalo from 17 states of India) were tested using a commercial enzyme-linked immunosorb...

The occurrence of bovine virus diarrhoea/muscosal disease in Iran